N-糖苷酶F(PNGaseF)是一種酰胺水解酶，經過和平空間站伊麗莎菌克隆，主要由腦膜炎膿桿菌等革蘭氏陰性菌分泌。酵母重組表達N-糖苷酶F（比活性：750000U/mL），可以裂解由天冬酰胺連接的高甘露糖、雜合和復雜的寡糖糖蛋白。PNGaseF的切割位點為糖蛋白內側N-乙酰葡萄糖胺（GlcNAc）和天冬酰氨殘基之間的酰胺鍵，同時將酶解后蛋白上的天冬氨酰轉化為天冬氨酸。本產品帶his標簽，常應用于抗體及其相關蛋白完全去糖基化。另外，我司還提供其他類型的糖苷酶，包括酵母重組表達的N-糖苷酶F，糖苷內切酶H，糖苷內切酶S。產品信息產品性質中文別名（Chinesesynonym）N-糖酰胺酶F；N-糖苷酶F英文別名（Englishsynonym）PNGaseF來源（Source）酵母重組表達分子量（Molecularweight）36kDa比活性（Specificactivity）750000U/mL緩沖液組分（Buffer）20mMTris-HClpH7.5,50mMNaCl,5mMEDTA,50%Glycerol（FGF-21）是FGF基因家族的成員。 基于其結構，FGF-21與FGF-19和-23一起進一步分為FGF的亞家族。Recombinant Human CDCP1 Protein,hFc Tag

Coronavirusesarecommonlycomprisedoffourstructuralproteins:Spikeprotein(S),Envelopeprotein(E),Membraneprotein(M)andNucleocapsidprotein(N).TheSARS-CoV-2Sproteinisaglycoproteinthatmediatesmembranefusionandviralentry.TheSproteinishomotrimeric,witheach~180-kDamonomerconsistingoftwosubunits,S1andS2.TheRBDofSARS-CoV-2bindsametallopeptidase,angiotensin-convertingenzyme2(ACE-2).產品性質別名SproteinRBD;SglycoproteinRBD;SpikeproteinRBDAccessionQHD43416.1表達區間及表達系統RecombinantSARS-CoV-2SpikeRBD(OmicronBA.4/BA.5/BA.5.1.3/BA.5.2)ProteinisexpressedfromExpi293withHistagattheC-terminal.ItcontainsArg319-Phe541(G339D,S371F,S373P,S375F,T376A,D405N,R408S,K417N,N440K,L452R,S477N,T478K,E484A,F486V,Q498R,N501Y,Y505H).Recombinant Cynomolgus NOGOR Protein,His TagPreScission Protease是一種由人鼻病毒14型的3C蛋白酶（human rhinovirus）和GST組成的融合蛋白。

產品簡介抑肽酶（Aprotinin），又稱為抑蛋白酶肽，是一種競爭性、可逆的絲氨酸蛋白酶抑制劑，可與絲氨酸蛋白酶形成穩定復合物并阻斷酶的活性位點，這種結合是可逆的，大多數的抑肽酶-蛋白酶復合物在極端的pH<3.0的條件下解除結合。抑肽酶抑制糜蛋白酶、胰蛋白酶、激肽釋放酶和血纖維蛋白溶酶，不能抑制Xa因子和凝血酶。從結構上來說，抑肽酶是一種來自牛肺的單體球狀蛋白，由58個氨基酸組成并排列在具有三個交聯二硫鍵的單個多肽鏈中。重組抑肽酶采用大腸桿菌表達，在GMP法規下生產，不含任何動物源成分，無動物源性的病毒污染，氨基酸序列與來源于牛肺的抑肽酶完全一致，具有與動物源性抑肽酶相同的酶學性質，可替代動物源性抑肽酶用于各種生物技術過程中，如：重組蛋白生產中抑制絲氨酸蛋白酶的活性；細胞培養等。另外，也提供來源于牛肺的抑肽酶（動物源性）酶活單位：能抑制1個胰蛋白酶單位的活力稱為1個抑肽酶活力單位（EPU）。儲存條件凍干粉2~8℃保存，有效期2年。使用方法抑肽酶與蛋白酶是等摩爾有效結合，推薦的結合pH>6.0，在pH<3.0的條件下不結合。可直接使用0.9%NaCl溶解，溶解后可-20℃儲存。

Angiotensin I Converting Enzyme (ACE-2), also called ACEH (ACE homologue), is a dimeric, zinc-dependent metalloprotease of the ACE family that also includes somatic and germinal ACE. ACE-2 mRNA is found at high levels in heart, testis, and kidney and at lower levels in a wide variety of tissues. ACE-2 is the SARS-CoV and SARS-CoV2 Spike protein receptor in vivo, functions catalytically as a carboxypeptidase to cleave several substrates including angiotensins I and II, and acts as a partner for B0AT1-family amino acid transporters. Through these functions, ACE-2 has been shown to be involved in several diseases including SARS, COVID19, acute lung injury, heart disease, liver and lung fibrosis, inflammatory lung disease, and cardiopulmonary disease . Full length ACE-2 protein includes an extracellular region composed of a single N-terminal peptidase domain and C-terminal collectrin-like domain (CLD), a transmembrane domain, and a short cytoplasmic tail. The N-terminal peptidase region is required for binding to SARS-CoV and SARS-CoV2 spike proteins, while the CLD contains a region that promotes dimerization and association with amino acid transporters.CX3CL1受到促炎性刺激的上調，包括巨噬細胞，樹突狀細胞，內皮細胞，神經元，平滑肌，上皮細胞的細胞類型。

Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling),hFc Tag性能參數分子別名（Synonyms）OX40Lreceptor;CD134;TNFRSF4;Ly-70表達區間及表達系統（Source）BiotinylatedHumanOX40/TNFRSF4/CD134Protein(PrimaryAmineLabeling)isexpressedfromHEK293withhFctagattheC-Terminus.ItcontainsLeu29-Ala216.[Accession|P43489]分子量大小（MolecularWeight）TheproteinhasapredictedMWof46.8kDa.Duetoglycosylation,theproteinmigratesto72-75kDabasedonSDS-PAGEresult.（Endotoxin）Lessthan1EUperμgbytheLALmethod.純度（Purity）>95%asdeterminedbySDS-PAGE制劑（Formulation）Suppliedas0.22μmfilteredsolutioninPBS(pH7.4).儲存條件Theproductshouldbestoredat-85~-65℃for1yearfromdateofreceipt.Recommendtoaliquottheproteinintosmallerquantitieswhenfirstusedandavoidrepeatedfreeze-thawcycles.α-凝血酶（α-Thrombin）可以啟動XIII因子和血小板，或者用作血管收縮劑。Recombinant Mouse BCHE/Butyrylcholinesterase Protein,His Tag

成纖維細胞生長因子18（FGF-18）是20 kDa蛋白，在骨骼發育和骨穩態中起著重要作用。Recombinant Human CDCP1 Protein,hFc Tag

SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that also include MERS?CoV and SARS-CoV-1. Coronaviruses are commonly comprised of four structural proteins: Spike protein (S), Envelope protein (E), Membrane protein (M) and Nucleocapsid protein (N). The SARS-CoV-2 S protein is a glycoprotein that mediates membrane fusion and viral entry. The S protein is homotrimeric, with each ~180-kDa monomer consisting of two subunits, S1 and S2 .The RBD of SARS-CoV-2 binds a metallopeptidase, angiotensin-converting enzyme 2 (ACE-2). Before binding to the ACE-2 receptor, structural analysis of the S1 trimer shows that only one of the three RBD domains is in the "up" conformation. This is an unstable and transient state that passes between trimeric subunits but is nevertheless an exposed state to be targeted for neutralizing antibody therapy. Polyclonal antibodies to the RBD of the SARS-CoV-2 protein have been shown to inhibit interaction with the ACE-2 receptor, confirming RBD as an attractive target for vaccinations or antiviral therapy.  Recombinant Human CDCP1 Protein,hFc Tag

浦斯瑞（上海）生物醫藥有限公司匯集了大量的優秀人才，集企業奇思，創經濟奇跡，一群有夢想有朝氣的團隊不斷在前進的道路上開創新天地，繪畫新藍圖，在江蘇省等地區的化工中始終保持良好的信譽，信奉著“爭取每一個客戶不容易，失去每一個用戶很簡單”的理念，市場是企業的方向，質量是企業的生命，在公司有效方針的領導下，全體上下，團結一致，共同進退，齊心協力把各方面工作做得更好，努力開創工作的新局面，公司的新高度，未來浦斯瑞（上海）生物醫藥供應和您一起奔向更美好的未來，即使現在有一點小小的成績，也不足以驕傲，過去的種種都已成為昨日我們只有總結經驗，才能繼續上路，讓我們一起點燃新的希望，放飛新的夢想！